Sodium Carbonate → 4-Oxo-2-nonenal

HRID 2191167노트

반응식

HRID 2191167 반응식
[CH2:1]([C:6]1[O:7][CH:8]=[CH:9][CH:10]=1)[CH2:2][CH2:3][CH2:4][CH3:5].ClC1C=CC=C(C(OO)=[O:19])C=1.C(=O)([O-])[O-].[Na+].[Na+]>ClCCl>[O:19]=[C:6]([CH2:1][CH2:2][CH2:3][CH2:4][CH3:5])/[CH:10]=[CH:9]/[CH:8]=[O:7]

참가 물질

5

반응물 3

HCID 10340Sodium CarbonateHCID 196022-PentylfuranHCID 70297m-Chloroperbenzoic acid

생성물 1

HCID 64455374-Oxo-2-nonenal수율 73%

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

2.0 g (14.47 mmol) of 2-pentylfuran was dissolved in 60 ml of dichloromethane, and 3.84 g (14.47 mmol) of 65% m-chloroperbenzoic acid was added dropwise thereto with stirring under ice-cooling, followed by stirring for 1 hour at the same temperature. To the reaction solution was added saturated aqueous sodium carbonate and the mixture was extracted with dichloromethane. The organic layer was washed with water, dried over anhydrous magnesium sulfate, and was then concentrated under reduced pressure to give 1.62 g of the title compound as a yellow oil (yield: 73%).

후처리

  1. temperaturecooling
  2. stirringby stirring for 1 hour at the same temperature
  3. extractionthe mixture was extracted with dichloromethane
  4. washThe organic layer was washed with water
  5. dry with materialdried over anhydrous magnesium sulfate
  6. concentrationwas then concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-14feb5106d584d0ea75c76b6171c5a7c
출처 데이터셋
uspto-grants-2012_12
특허 번호
USRE043858E1

반응 노트

불러오는 중…