HCID 58241683, 화합물 → HCID 58241679, 화합물

HRID 2191200노트

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HRID 2191200 반응식
[CH3:1][O:2][C:3]1[C:8]([N+:9]([O-])=O)=[CH:7][CH:6]=[C:5]([O:12][CH3:13])[C:4]=1[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=1[CH3:20]>CO.[Pd]>[CH3:1][O:2][C:3]1[C:8]([NH2:9])=[CH:7][CH:6]=[C:5]([O:12][CH3:13])[C:4]=1[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=1[CH3:20]

참가 물질

4

반응물 1

HCID 58241683HCID 58241683, 화합물

생성물 1

HCID 58241679HCID 58241679, 화합물수율 78.8%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매

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온도
50 °C

실험 절차

Pd/C (0.1 g) was added to 2,6-dimethoxy-2′-methyl-3-nitrobiphenyl (0.2 g, 0.73 mmol) in methanol (20 ml), and under 1 atm of H2, the mixture was heated at 50° C. for 2 h. Filtration and concentration gave 2,6-dimethoxy-2′-methylbiphenyl-3-ylamine (0.14 g) as a colorless oil, which was directly reacted further.

후처리

  1. filtrationFiltration and concentration

출처 및 근거

ORD 기록
ord-8bbdcd429f5848d88ba293f1e56a8145
출처 데이터셋
uspto-grants-2012_12
특허 번호
US08329619B2

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