Acetic Acid → HCID 14674517, 화합물

HRID 21919노트

반응식

HRID 21919 반응식
[CH2:1]1[CH2:36][O:35][C:3]([CH2:30][CH2:31][CH2:32][CH2:33][CH3:34])([CH2:4][CH2:5][C:6]23[CH2:13][CH:12]([O:14][C:15](=[O:28])[C:16]4C=CC(C5C=CC=CC=5)=CC=4)[CH2:11][CH:10]2CC(=O)O3)[O:2]1.C(=O)([O-])[O-:38].[K+].[K+].C(O)(=O)C>CO>[CH2:36]1[CH2:1][O:2][C:3]([CH2:30][CH2:31][CH2:32][CH2:33][CH3:34])([CH2:4][CH2:5][C@H:6]2[C@H:10]([OH:38])[CH2:11][C@H:12]3[C@@H:13]2[CH2:16][C:15](=[O:28])[O:14]3)[O:35]1

참가 물질

5

반응물 3

HCID 176Acetic AcidHCID 11430Potassium CarbonateHCID 867458653,3-Ethylenedioxyoctyl-7-(4-phenylbenzoyloxy)-2-oxabicyclo[3.3.0]octan-3-one

생성물 1

HCID 14674517HCID 14674517, 화합물

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

To a solution of (1S,5R,6R,7R)-6-(3,3-ethylenedioxyoctyl-7-(4-phenylbenzoyloxy)-2-oxabicyclo[3.3.0]octan-3-one (5a) (8.20 g) in methanol (200 ml) was added potassium carbonate (1.15 g) and the resultant mixture was stirred overnight, and acetic acid (1 ml) was added thereto. The crude product obtained by treating in the conventional manner was subjected to silica gel column chromatography to give the title compound (6a).

후처리

  1. customThe crude product obtained
  2. additionby treating in the conventional manner

출처 및 근거

ORD 기록
ord-ed217e2ec3674e7a8d8214038dadb11e
출처 데이터셋
uspto-grants-1995_06
특허 번호
US05426115

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