Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Imidazole → 5-(t-Butyldimethylsiloxy)-3-pentyne
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Imidazole | HCID 795 | — |
| 반응물 | 3-Butyn-1-OL | HCID 13566 | — |
| 반응물 | tert-Butyldimethylsilyl chloride | HCID 28928 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 5-(t-Butyldimethylsiloxy)-3-pentyne | HCID 11019857 | — |
반응 단계
To a solution of 3-butyn-1-ol (g) (10.0 g) in DMF (80 ml) were added t-butyldimethylsilyl chloride (21.5 g) and imidazol (10.6 g), and the resultant mixture was kept at 35° C. for 7 hours. The reaction mixture was treated in the conventional manner and the obtained crude product was distilled to give the title compound (h).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05426115 |
| 출처 데이터셋 | uspto-grants-1995_06 |
| ORD ID | ord-f6de6665a81f41a69e382a42c905148e |
| 출처 메모 | uspto-grants-1995_06 |