Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N,N-Dimethylacrylamide → (E)-4-Ethoxy-3-(1-methyl-7-oxo-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-5-yl)cinnamic acid dimethylamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N,N-Dimethylacrylamide | HCID 17587 | — |
| 반응물 | 5-(5-Bromo-2-ethoxyphenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-D]pyrimidin-7(6H)-one | HCID 135738554 | — |
| 생성물 | (E)-4-Ethoxy-3-(1-methyl-7-oxo-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-5-yl)cinnamic acid dimethylamide | HCID 136401237 | — |
반응 단계
The title compound was prepared from N,N-dimethylacrylamide and 5-(5-bromo-2-ethoxyphenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one following the procedure of Example 19 and was obtained, following crystallisation from ethyl acetate-hexane, as colourless crystals (38%), m.p. 219°-221° C. Found: C,64.15; H,6.46; N,16.96. C22H27N5O3 requires C,64.53; H,6.65; N,17.10%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05426107 |
| 출처 데이터셋 | uspto-grants-1995_06 |
| ORD ID | ord-a2be3b7853fd422ea0419f6f2130e228 |
| 출처 메모 | uspto-grants-1995_06 |