4-Chloropyridine-3-sulfonyl chloride → HCID 59577911, 화합물

HRID 2194180노트

반응식

HRID 2194180 반응식
[F:1][C:2]([F:22])([F:21])[O:3][C:4]1[CH:9]=[CH:8][C:7]([N:10]2[CH2:14][CH2:13][C:12]3([CH2:19][CH2:18][NH:17][CH2:16][CH2:15]3)[C:11]2=[O:20])=[CH:6][CH:5]=1.[Cl:23][C:24]1[CH:29]=[CH:28][N:27]=[CH:26][C:25]=1[S:30](Cl)(=[O:32])=[O:31]>>[Cl:23][C:24]1[CH:29]=[CH:28][N:27]=[CH:26][C:25]=1[S:30]([N:17]1[CH2:16][CH2:15][C:12]2([C:11](=[O:20])[N:10]([C:7]3[CH:8]=[CH:9][C:4]([O:3][C:2]([F:1])([F:21])[F:22])=[CH:5][CH:6]=3)[CH2:14][CH2:13]2)[CH2:19][CH2:18]1)(=[O:32])=[O:31]

참가 물질

3

반응물 2

HCID 64222234-Chloropyridine-3-sulfonyl chlorideHCID 667427592-(4-(Trifluoromethoxy)phenyl)-2,8-diazaspiro[4.5]decan-1-one

생성물 1

HCID 59577911HCID 59577911, 화합물

실험 절차

The title compound was prepared in analogy to example 180 step D from 2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one (described in example 180 step C) and 4-chloro-pyridine-3-sulfonyl chloride. Off-white solid. MS (ESI): 490.2 (MH+).

출처 및 근거

ORD 기록
ord-ffacbedce57343a191658d922ae19244
출처 데이터셋
uspto-grants-2012_12
특허 번호
US08329904B2

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