5-chloro-2-(2-methoxyethyl)pyridazin-3(2H)-one → 2-(2-methoxy-ethyl)-5-(4-iodo-2-methyl-imidazol-1-yl)-2H-pyridazin-3-one

반응식

Cl[C:2]1[CH:7]=[N:6][N:5]([CH2:8][CH2:9][O:10][CH3:11])[C:4](=[O:12])[CH:3]=1.[I:13][C:14]1[N:15]=[C:16]([CH3:19])[NH:17][CH:18]=1>>[CH3:11][O:10][CH2:9][CH2:8][N:5]1[C:4](=[O:12])[CH:3]=[C:2]([N:17]2[CH:18]=[C:14]([I:13])[N:15]=[C:16]2[CH3:19])[CH:7]=[N:6]1

참가 물질

반응물 2

HCID 668667375-chloro-2-(2-methoxyethyl)pyridazin-3(2H)-one

HCID 178433060HCID 178433060, 화합물

생성물 1

HCID 668651282-(2-methoxy-ethyl)-5-(4-iodo-2-methyl-imidazol-1-yl)-2H-pyridazin-3-one

실험 절차

The title compound, light yellow oil, MS: m/e=361.1 (M+H+), was prepared in accordance with the general method of example 23b from 5-chloro-2-(2-methoxy-ethyl)-2H-pyridazin-3-one and 4-Iodo-2-methyl-1H-imidazole.

출처 및 근거

ORD 기록: ord-b3943155cde34366949224b41547213e
출처 데이터셋: uspto-grants-2012_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08334287B2

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