4-Aminotricyclo[3.3.1.13,7]decane-1-methanol → 3-[2-(1-Cyclopropanesulfonyl-piperidin-4-yl)-ethoxy]-N-(5-hydroxymethyl-adamantan-2-yl)benzamide
반응식
[CH:1]1([S:4]([N:7]2[CH2:12][CH2:11][CH:10]([CH2:13][CH2:14][O:15][C:16]3[CH:17]=[C:18]([CH:22]=[CH:23][CH:24]=3)[C:19]([OH:21])=O)[CH2:9][CH2:8]2)(=[O:6])=[O:5])[CH2:3][CH2:2]1.[NH2:25][CH:26]1[CH:33]2[CH2:34][C:29]3([CH2:36][OH:37])[CH2:30][CH:31]([CH2:35][CH:27]1[CH2:28]3)[CH2:32]2>>[CH:1]1([S:4]([N:7]2[CH2:12][CH2:11][CH:10]([CH2:13][CH2:14][O:15][C:16]3[CH:17]=[C:18]([CH:22]=[CH:23][CH:24]=3)[C:19]([NH:25][CH:26]3[CH:27]4[CH2:35][CH:31]5[CH2:30][C:29]([CH2:36][OH:37])([CH2:34][CH:33]3[CH2:32]5)[CH2:28]4)=[O:21])[CH2:9][CH2:8]2)(=[O:6])=[O:5])[CH2:3][CH2:2]1참가 물질
3
실험 절차
Prepared from 3-[2-(1-cyclopropanesulfonyl-piperidin-4-yl)-ethoxy]-benzoic acid and 4-amino-1-hydroxymethyladamantane to give the title compound as a mixture of two isomers.
출처 및 근거
- ORD 기록
- ord-d05230ac47744acd8700cbc626285ab2
- 출처 데이터셋
- uspto-grants-2012_12