Cyclohexene → 2-amino-5-(2,6-dimethyl-4-morpholinyl)Benzoic acid
반응식
[N+:1]([C:4]1[CH:12]=[CH:11][C:10]([N:13]2[CH2:18][CH:17]([CH3:19])[O:16][CH:15]([CH3:20])[CH2:14]2)=[CH:9][C:5]=1[C:6]([OH:8])=[O:7])([O-])=O.C1CCCCC=1>[Pd]>[NH2:1][C:4]1[CH:12]=[CH:11][C:10]([N:13]2[CH2:18][CH:17]([CH3:19])[O:16][CH:15]([CH3:20])[CH2:14]2)=[CH:9][C:5]=1[C:6]([OH:8])=[O:7]참가 물질
4
실험 절차
The mixture of 6 g 2-nitro-5-(2,6-dimethylmorpholin-4-yl)benzoic acid, 15 ml cyclohexene and 3 g Pd/C (10%) is heated under reflux for 6 hours. The hot reaction mixture is filtered through a celite pad. After evaporation of the filtrate 4.8 g title product is obtained (MH+: 251).
후처리
- temperatureis heated
- temperatureunder reflux for 6 hours
- filtrationThe hot reaction mixture is filtered through a celite pad
- customAfter evaporation of the filtrate 4.8 g title product
- customis obtained (MH+: 251)
출처 및 근거
- ORD 기록
- ord-433cddb174df4f15ace534a9d53a86bf
- 출처 데이터셋
- uspto-grants-2012_12
- 특허 번호
- US08338411B2
반응 노트
불러오는 중…