tert-Butyl piperazine-1-carboxylate → HCID 23627510, 화합물

반응식

Br[C:2]1[CH:10]=[C:9]2[C:5]([C:6]([CH2:16][CH3:17])=[N:7][N:8]2[CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[CH:4][CH:3]=1.C([N:25]1[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]1)(OC(C)(C)C)=O>>[CH:11]1([N:8]2[C:9]3[C:5](=[CH:4][CH:3]=[C:2]([N:25]4[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]4)[CH:10]=3)[C:6]([CH2:16][CH3:17])=[N:7]2)[CH2:15][CH2:14][CH2:13][CH2:12]1

참가 물질

반응물 2

HCID 143452tert-Butyl piperazine-1-carboxylate

HCID 22733808HCID 22733808, 화합물

생성물 1

HCID 23627510HCID 23627510, 화합물

실험 절차

Prepared by the method outlined for Example 1 using 6-bromo-1-cyclopentyl-3-ethyl-1H-indazole (CAS [199172-02-6]) as the aryl halide and N BOC-piperazine as the amine component. Oil and gum (88% for two steps). LC/MS 4.56 min, [M+1]+ 299.

후처리

customPrepared by the method
customLC/MS 4.56 min, [M+1]+ 299

출처 및 근거

ORD 기록: ord-a2888f03940f45f5bc70b1c8e56cf959
출처 데이터셋: uspto-grants-2012_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08338405B2

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