Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(5-amino-2,3-dihydro-1H-indol-1-yl)ethan-1-one → 1-Acetylindoline-6-carbonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(5-amino-2,3-dihydro-1H-indol-1-yl)ethan-1-one | HCID 292507 | — |
| 반응물 | 1-Acetylindoline-5-carbonitrile | HCID 18526421 | — |
| 생성물 | 1-Acetylindoline-6-carbonitrile | HCID 67317991 | — |
반응 단계
The title compound was prepared following the procedure described for 1-acetoylindoline-5-carbonitrile but starting from 1-(5-aminoindolin-1-yl)ethanone (Aldrich, 844 mg; 4.79 mmol), to give 1-acetoylindoline-6-carbonitrile as an orange solid. 1H NMR: (DMSO-d6, 400 MHz) δ 8.31 (1H, s), 7.52-7.45 (2H, m), 4.18 (2H, t, J=8.6 Hz), 3.32-3.23 (2H, m), 2.23 (3H, s).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08202856B2 |
| 출처 데이터셋 | uspto-grants-2012_06 |
| ORD ID | ord-06532395c5884f73a9e0f81f462d5f9b |
| 출처 메모 | uspto-grants-2012_06 |