Di-tert-butyl 1-(5-cyanothiophen-2-yl)hydrazine-1,2-dicarboxylate → HCID 69090430, 화합물

HRID 2196510노트

반응식

HRID 2196510 반응식
[ClH:1].N(C1C=C(C#N)SC=1)N.[C:11]([C:13]1[S:17][C:16]([N:18](C(OC(C)(C)C)=O)[NH:19]C(OC(C)(C)C)=O)=[CH:15][CH:14]=1)#[N:12]>>[Cl-:1].[C:11]([C:13]1[S:17][C:16]([NH2+:18][NH2:19])=[CH:15][CH:14]=1)#[N:12]

참가 물질

3

반응물 2

HCID 59843233Di-tert-butyl 1-(5-cyanothiophen-2-yl)hydrazine-1,2-dicarboxylateHCID 69299496HCID 69299496, 화합물

생성물 1

HCID 69090430HCID 69090430, 화합물수율 78%

실험 절차

Following the same procedure as described for compound 13 (step 3, scheme 2, example 1c) except using 20 (692 mg, 2.04 mmol) instead of 12 to afford 21 (278 mg, 78%) as a brown solid. LRMS (ESI): calc. 139.0; found 140.1 (MH)+.

출처 및 근거

ORD 기록
ord-38a1cb427a69415090af08e47c5bfba8
출처 데이터셋
uspto-grants-2012_12
특허 번호
US08338437B2

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