Ethylamine → (2'-Ethylaminomethyl-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester

HRID 2197346노트

반응식

[CH3:1][O:2][C:3](=[O:23])[CH2:4][C:5]1[CH:6]=[C:7]([C:11]2[CH:16]=[CH:15][C:14]([C:17]([F:20])([F:19])[F:18])=[CH:13][C:12]=2[CH:21]=O)[CH:8]=[CH:9][CH:10]=1.[CH2:24]([NH2:26])[CH3:25]>>[CH3:1][O:2][C:3](=[O:23])[CH2:4][C:5]1[CH:6]=[C:7]([C:11]2[CH:16]=[CH:15][C:14]([C:17]([F:19])([F:20])[F:18])=[CH:13][C:12]=2[CH2:21][NH:26][CH2:24][CH3:25])[CH:8]=[CH:9][CH:10]=1

참가 물질

반응물 2

HCID 6341Ethylamine

HCID 86633174HCID 86633174, 화합물

생성물 1

HCID 66604353(2'-Ethylaminomethyl-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester

실험 절차

Prepared according to the procedure described in Example 1, Step 5, using the following starting materials: (2′-formyl-4′-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester and ethylamine (2M in THF).

후처리

customPrepared

출처 및 근거

ORD 기록: ord-5fbc5267a4e9498a81ad00086ca48cb5
출처 데이터셋: uspto-grants-2012_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08338484B2

반응 노트

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