참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | methyl-(S)-4-(1-carbamoylpropylamino)butyrate | HCID 57424277 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | Levetiracetam | HCID 5284583 | — |
반응 단계
To the crude methyl-(S)-4-(1-carbamoylpropylamino)butyrate (VIg) in toluene (25 ml) is added hydroxypyrridine (0.7 g, 30 mol %). The mixture is heated to 92° C. until complete conversion. After 17 hours the mixture is concentrated to dryness to yield (S)-2-(2-oxopyrrolidin-1-yl)butyramide.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08338621B2 |
|---|
| 출처 데이터셋 | uspto-grants-2012_12 |
|---|
| ORD ID | ord-35ad66a7b70145298ece2ce43a329ddb |
|---|
| 출처 메모 | uspto-grants-2012_12 |
|---|
