참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Diphenyl Ether | HCID 7583 | — |
| 반응물 | Diethyl [[(6-methyl-2-pyridyl)amino]methylene]malonate | HCID 83264 | — |
| 용매 | Hexane | HCID 8058 | — |
| 생성물 | Ethyl 7-methyl-4-oxo-1,8-naphthyridine-3-carboxylate | HCID 5373687 | 71% |
반응 단계
A solution of diphenyl ether was heated to 250° C. and the product of Example 1a (2.50 g, 9.0 mmol) was added in several small portions over a period of about 5 min then heated at 250° C. for 30 min. After cooling to room temperature diluted with hexane. The resulting solid was filtered and was dried under vacuum giving the title compound as a tan solid (1.47 g, 71%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08338605B2 |
|---|
| 출처 데이터셋 | uspto-grants-2012_12 |
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| ORD ID | ord-a1d2c090bb7344c68a13d0d54f93a80e |
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| 출처 메모 | uspto-grants-2012_12 |
|---|
