Acetyl chloride → N-[3-(4-Methyl-2-nitro-phenylsulfanyl)-phenyl]-acetamide
반응식
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9]2[CH:10]=[C:11]([NH2:15])[CH:12]=[CH:13][CH:14]=2)=[C:4]([N+:16]([O-:18])=[O:17])[CH:3]=1.[C:19](Cl)(=[O:21])[CH3:20]>C(Cl)Cl>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9]2[CH:10]=[C:11]([NH:15][C:19](=[O:21])[CH3:20])[CH:12]=[CH:13][CH:14]=2)=[C:4]([N+:16]([O-:18])=[O:17])[CH:3]=1참가 물질
4
실험 절차
The product from Example 71a (650 mg, 2.50 mmol) was dissolved in DCM and acetyl chloride (196 mg, 2.50 mmol) was added. Allowed to stir at room temperature for 1 h, at which time a solid was collected by filtration providing the title compound (690 mg, 61%)
후처리
- filtrationwas collected by filtration
출처 및 근거
- ORD 기록
- ord-c2cf9e3e33ed42098db81a986eadde3a
- 출처 데이터셋
- uspto-grants-2012_12
- 특허 번호
- US08338605B2
반응 노트
불러오는 중…