Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl 5-bromopyridine-3-carboxylate → Methyl 5-(4-(trifluoromethyl)phenyl)nicotinate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl 5-bromopyridine-3-carboxylate | HCID 699336 | — |
| 반응물 | 4-(Trifluoromethyl)phenylboronic acid | HCID 2734389 | — |
| 생성물 | Methyl 5-(4-(trifluoromethyl)phenyl)nicotinate | HCID 20099855 | — |
반응 단계
According to General Method 3A, 28 g (132 mmol) of methyl 5-bromonicotinate and 30 g (158 mmol, 1.2 eq.) of 4-trifluoromethylphenylboronic acid were reacted. Yield: 32 g (85% of theory)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08202862B2 |
| 출처 데이터셋 | uspto-grants-2012_06 |
| ORD ID | ord-bdf78bc2be8049e0b993b65f6f54d99e |
| 출처 메모 | uspto-grants-2012_06 |