Benzyl Bromide → Methyl 2-(4-(benzyloxy)-3-bromophenyl)acetate

HRID 2200390노트

반응식

HRID 2200390 반응식
[Br:1][C:2]1[CH:3]=[C:4]([CH2:9][C:10]([O:12][CH3:13])=[O:11])[CH:5]=[CH:6][C:7]=1[OH:8].C(=O)([O-])[O-].[K+].[K+].[CH2:20](Br)[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>CC(C)=O>[Br:1][C:2]1[CH:3]=[C:4]([CH2:9][C:10]([O:12][CH3:13])=[O:11])[CH:5]=[CH:6][C:7]=1[O:8][CH2:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1

참가 물질

5

반응물 3

HCID 7498Benzyl BromideHCID 11430Potassium CarbonateHCID 10634081Methyl 2-(3-bromo-4-hydroxyphenyl)acetate

생성물 1

HCID 56605342Methyl 2-(4-(benzyloxy)-3-bromophenyl)acetate

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

Compound 10 (12.3 g) was dissolved in 100 mL acetone and 7.6 g of potassium carbonate was added. 8.6 g of benzyl bromide was added with stirring. The solid was removed by suction filtration and the liquid was evaporated to product 11.

후처리

  1. customThe solid was removed by suction filtration
  2. customthe liquid was evaporated to product 11

출처 및 근거

ORD 기록
ord-d183db3ee6454f69b0c850e9b2968b79
출처 데이터셋
uspto-grants-2016_06
특허 번호
US09359372B2

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