Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → (S)-methyl 2-(2-amino-4-methylpentanamido)acetate hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | methyl 2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-4-methylpentanamido]acetate | HCID 6560406 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | (S)-methyl 2-(2-amino-4-methylpentanamido)acetate hydrochloride | HCID 18603049 | — |
반응 단계
To a solution of (S)-methyl 2-(2-((tert-butoxycarbonyl)amino)-4-methylpentanamido) acetate (3w) in 1,4-dioxane was added a 5M solution of HCl in 1,4-dioxane at room temperature. The reaction was stirred at room temperature for 16 h. The reaction mixture was filtered to afford (S)-methyl 2-(2-amino-4-methylpentanamido)acetate hydrochloride (4w) as the filtered solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09365498B2 |
| 출처 데이터셋 | uspto-grants-2016_06 |
| ORD ID | ord-2252f31280bf45b8a8a34205320c0bf4 |
| 출처 메모 | uspto-grants-2016_06 |