Acetyl chloride → N-(1H-pyrrolo[3,2-c]pyridin-4-yl)acetamide

HRID 2201797노트

반응식

HRID 2201797 반응식
[NH2:1][C:2]1[C:7]2[CH:8]=[CH:9][N:10](C(OCC3C=CC=CC=3)=O)[C:6]=2[CH:5]=[CH:4][N:3]=1.[C:21](Cl)(=[O:23])[CH3:22]>>[NH:10]1[C:6]2[CH:5]=[CH:4][N:3]=[C:2]([NH:1][C:21](=[O:23])[CH3:22])[C:7]=2[CH:8]=[CH:9]1

참가 물질

3

반응물 2

HCID 6367Acetyl chlorideHCID 71061834benzyl 4-amino-1H-pyrrolo[3,2-c]pyridine-1-carboxylate

생성물 1

HCID 86720630N-(1H-pyrrolo[3,2-c]pyridin-4-yl)acetamide

실험 절차

N-(1H-pyrrolo[3,2-c]pyridin-4-yl)acetamide (Intermediate 25) was prepared from benzyl 4-amino-1H-pyrrolo[3,2-c]pyridine-1-carboxylate in an analogous manner using acetyl chloride.

출처 및 근거

ORD 기록
ord-ce4d8548406f45e19942faf4f0b58831
출처 데이터셋
uspto-grants-2016_06
특허 번호
US09364466B2

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