N-(1H-Pyrrolo[2,3-c]pyridin-7-yl)acetamide → N-[3-(4-Cyano-2,6-difluorobenzoyl)-1H-pyrrolo[2,3-c]pyridin-7-yl]acetamide

HRID 2201841노트

반응식

HRID 2201841 반응식
[NH:1]1[C:5]2=[C:6]([NH:10][C:11](=[O:13])[CH3:12])[N:7]=[CH:8][CH:9]=[C:4]2[CH:3]=[CH:2]1.[C:14]([C:16]1[CH:24]=[C:23]([F:25])[C:19]([C:20](Cl)=[O:21])=[C:18]([F:26])[CH:17]=1)#[N:15]>>[C:14]([C:16]1[CH:17]=[C:18]([F:26])[C:19]([C:20]([C:3]2[C:4]3[C:5](=[C:6]([NH:10][C:11](=[O:13])[CH3:12])[N:7]=[CH:8][CH:9]=3)[NH:1][CH:2]=2)=[O:21])=[C:23]([F:25])[CH:24]=1)#[N:15]

참가 물질

3

반응물 2

HCID 86720620N-(1H-Pyrrolo[2,3-c]pyridin-7-yl)acetamideHCID 867206254-Cyano-2,6-difluorobenzoyl chloride

생성물 1

HCID 86720649N-[3-(4-Cyano-2,6-difluorobenzoyl)-1H-pyrrolo[2,3-c]pyridin-7-yl]acetamide

실험 절차

N-[3-(4-Cyano-2,6-difluorobenzoyl)-1H-pyrrolo[2,3-c]pyridin-7-yl]acetamide (Compound No. 53) was prepared from N-(1H-pyrrolo[2,3-c]pyridin-7-yl)acetamide and 4-cyano-2,6-difluoro benzoyl chloride.

출처 및 근거

ORD 기록
ord-8a93be4b75a84b24a35f7feeb97ce1f8
출처 데이터셋
uspto-grants-2016_06
특허 번호
US09364466B2

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