Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
[2-(2-Amino-3-methoxy-phenylcarbamoyl)-ethyl]-methyl-carbamic acid tert.-butyl ester → HCID 178488952, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | [2-(2-Amino-3-methoxy-phenylcarbamoyl)-ethyl]-methyl-carbamic acid tert.-butyl ester | HCID 68411798 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | HCID 178488952 | HCID 178488952 | 75.6% |
반응 단계
A solution of 2.1 g of crude [2-(2-amino-3-methoxy-phenylcarbamoyl)-ethyl]-methyl-carbamic acid tert.-butyl ester in 10 mL acetic acid was heated at 65° C. for 2 h. The reaction mixture was concentrated and purified by CC with EtOAc to yield 1.5 g of [2-(7-methoxy-1H-benzoimidazol-2-yl)-ethyl]-methyl-carbamic acid tert.-butyl ester as orange foam.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08202885B2 |
| 출처 데이터셋 | uspto-grants-2012_06 |
| ORD ID | ord-2221cab70cb74afabc02b086ed5cf267 |
| 출처 메모 | uspto-grants-2012_06 |