A mixture of 297 mg of a known compound (±)-4-[(4-methoxyphenyl)phenylmethoxy]piperidine, 240 mg of a known compound ethyl 2-chloromethylisonicotinate, 2.3 mL of acetonitrile, and 0.28 mL of triethylamine was stirred overnight. The mixture was poured into salt water and extracted with ethyl acetate. The extract was washed with a saturated saline solution and dried over sodium sulfate. The solvent was distilled off, and then the residue was purified by p-TLC to give the title compound (309 mg (67%)).
