3-(Trifluoromethoxy)benzene-1,2-diamine → Methyl-[3-(4-trifluoromethoxy-1H-benzoimidazol-2-yl)-propyl]-amine

HRID 220273

반응식

HRID 220273 반응식
[F:1][C:2]([F:13])([F:12])[O:3][C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([NH2:10])[C:5]=1[NH2:11].CO[C:16]1C(OC)=C[C:19]2[NH:20][C:21](CCCNC)=N[C:18]=2[CH:17]=1>>[CH3:21][NH:20][CH2:19][CH2:18][CH2:17][C:16]1[NH:10][C:6]2[CH:7]=[CH:8][CH:9]=[C:4]([O:3][C:2]([F:12])([F:13])[F:1])[C:5]=2[N:11]=1

참가 물질

3

반응물 2

HCID 140115773-(Trifluoromethoxy)benzene-1,2-diamineHCID 61363740[3-(5,6-dimethoxy-1H-benzoimidazol-2-yl)-propyl]-methyl-amine

생성물 1

HCID 68413403Methyl-[3-(4-trifluoromethoxy-1H-benzoimidazol-2-yl)-propyl]-amine

실험 절차

Prepared from 3-trifluoromethoxy-benzene-1,2-diamine in analogy to the methods described for [3-(5,6-dimethoxy-1H-benzoimidazol-2-yl)-propyl]-methyl-amine.

출처 및 근거

ORD 기록
ord-e6d4a31306514eaab307fe1aa1ee0d0e
출처 데이터셋
uspto-grants-2012_06
특허 번호
US08202885B2

연결된 노트

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