Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Anhydride → N-(2-Chloro-5-methoxyphenyl)acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Anhydride | HCID 7918 | — |
| 반응물 | 6-Chloro-m-anisidine | HCID 75460 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | N-(2-Chloro-5-methoxyphenyl)acetamide | HCID 19081918 | — |
반응 단계
To a solution of 10.59 g of 2-chloro-5-methoxyaniline in 50 mL of AcOH were added dropwise at 0° C. 6.8 mL of acetic anhydride. The reaction mixture was allowed to warm up to rt, stirred for 6 h and concentrated in vacuo. The crude product was purified by CC using EtOAc/heptane 1/3 to yield 13.0 g of N-(2-chloro-5-methoxy-phenyl)-acetamide as white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08202885B2 |
| 출처 데이터셋 | uspto-grants-2012_06 |
| ORD ID | ord-6bdd3efc020643ea87201df1f991d82f |
| 출처 메모 | uspto-grants-2012_06 |