1-Phenyl-1,2-propanedione → 3-[4-Methyl-5-phenyl-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-propionic acid

HRID 220289

반응식

HRID 220289 반응식
[C:1]1([C:7]2[N:8]=[C:9]([CH2:26][CH2:27][C:28]([OH:30])=[O:29])[N:10]([CH2:18][O:19][CH2:20][CH2:21][Si:22]([CH3:25])([CH3:24])[CH3:23])[C:11]=2[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)C=CC=CC=1.C1(C(=O)C(=O)C)C=CC=CC=1>>[CH3:1][C:7]1[N:8]=[C:9]([CH2:26][CH2:27][C:28]([OH:30])=[O:29])[N:10]([CH2:18][O:19][CH2:20][CH2:21][Si:22]([CH3:23])([CH3:25])[CH3:24])[C:11]=1[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

참가 물질

3

반응물 2

HCID 113631-Phenyl-1,2-propanedioneHCID 684143723-[4,5-diphenyl-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-propionic acid

생성물 1

HCID 684125043-[4-Methyl-5-phenyl-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-propionic acid

실험 절차

Prepared in analogy to the methods described for 3-[4,5-diphenyl-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-propionic acid replacing benzil with 1-phenyl-propane-1,2-dione.

후처리

  1. customPrepared in analogy to the methods

출처 및 근거

ORD 기록
ord-f4478e32d21b4b76bfc6bb5ac490f448
출처 데이터셋
uspto-grants-2012_06
특허 번호
US08202885B2

연결된 노트

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