Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Piperazine → 1-(3-Bromopyridin-2-yl)piperazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Piperazine | HCID 4837 | — |
| 반응물 | 3-Bromo-2-chloropyridine | HCID 693324 | — |
| 생성물 | 1-(3-Bromopyridin-2-yl)piperazine | HCID 13298529 | — |
반응 단계
Alternatively, 3-bromo-2-chloropyridine may be used as shown in Scheme VIII. Thus, 3-bromo-2-chloropyridine (27) is heated with piperazine to provide 1-(3-bromopyridin-2-yl)piperazine (28), followed by Suzuki coupling of the phenyl moiety to provide the phenylpiperazine intermediate (25).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08202873B2 |
| 출처 데이터셋 | uspto-grants-2012_06 |
| ORD ID | ord-2f53b5e6ae9c4b2fb35ad0ac6d14c993 |
| 출처 메모 | uspto-grants-2012_06 |