4-Amino-2-hydroxy-5-nitrobenzoic acid → 4,5-Diamino-2-hydroxybenzoic acid

HRID 2205118노트

반응식

HRID 2205118 반응식
[NH2:1][C:2]1[C:10]([N+:11]([O-])=O)=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[C:4]([OH:14])[CH:3]=1>CC(O)=O.[Pd]>[NH2:1][C:2]1[C:10]([NH2:11])=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[C:4]([OH:14])[CH:3]=1

참가 물질

4

반응물 1

HCID 218421914-Amino-2-hydroxy-5-nitrobenzoic acid

생성물 1

HCID 131586084,5-Diamino-2-hydroxybenzoic acid

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 176Acetic Acid용매

실험 절차

Under an H2(g) atmosphere, a suspension of 4-amino-2-hydroxy-5-nitrobenzoic acid (200 mg, 1.01 mmol, 1.00 equiv) and Pd/C (anhydrous) (0.1 g) in HOAc (15 mL) in a 50-mL round-bottom flask was allowed to react, with stirring, overnight at room temperature. The resulting solution was directly taken on to the next step without further purification.

후처리

  1. customto react
  2. customThe resulting solution was directly taken on to the next step without further purification

출처 및 근거

ORD 기록
ord-c8e11cca5aa645de84043ab848f77ef1
출처 데이터셋
uspto-grants-2016_06
특허 번호
US09370522B2

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