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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 220633생성일: 2026년 10월 26일

Hydrochloric Acid → 2-Nitro-1-[3-(trifluoromethyl)phenyl]ethanamine hydrochloride

https://huagongshe.com/reaction/220633

반응식

참여 물질

역할이름HCID투입량
반응물Hydrochloric AcidHCID 313—
반응물tert-Butyl {2-nitro-1-[3-(trifluoromethyl)phenyl]ethyl}carbamateHCID 59536870—
용매1,4-DioxaneHCID 31275—
생성물2-Nitro-1-[3-(trifluoromethyl)phenyl]ethanamine hydrochlorideHCID 68646447—

반응 단계

Of the compound from Example 12A, 340 mg (1.02 mmol) were admixed at RT with 6.8 ml of a 4N solution of hydrogen chloride in dioxane, and stirred for 1 h. The reaction mixture was concentrated under reduced pressure and dried in an HV. This gave 274 mg (99% of theory) of the title compound.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08202895B2
출처 데이터셋uspto-grants-2012_06
ORD IDord-9f140f45327940efaf8114ff642eb124
출처 메모uspto-grants-2012_06