Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 2-Nitro-1-[3-(trifluoromethyl)phenyl]ethanamine hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | tert-Butyl {2-nitro-1-[3-(trifluoromethyl)phenyl]ethyl}carbamate | HCID 59536870 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | 2-Nitro-1-[3-(trifluoromethyl)phenyl]ethanamine hydrochloride | HCID 68646447 | — |
반응 단계
Of the compound from Example 12A, 340 mg (1.02 mmol) were admixed at RT with 6.8 ml of a 4N solution of hydrogen chloride in dioxane, and stirred for 1 h. The reaction mixture was concentrated under reduced pressure and dried in an HV. This gave 274 mg (99% of theory) of the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08202895B2 |
| 출처 데이터셋 | uspto-grants-2012_06 |
| ORD ID | ord-9f140f45327940efaf8114ff642eb124 |
| 출처 메모 | uspto-grants-2012_06 |