Ethyl 4-piperidinecarboxylate → 1-(Cyclopropylmethyl)piperidine-4-carboxylic acid

HRID 220802노트

반응식

HRID 220802 반응식
[CH:1]1([CH:4]=O)[CH2:3][CH2:2]1.[NH:6]1[CH2:16][CH2:15][CH:9]([C:10]([O:12]CC)=[O:11])[CH2:8][CH2:7]1>>[CH:1]1([CH2:4][N:6]2[CH2:7][CH2:8][CH:9]([C:10]([OH:12])=[O:11])[CH2:15][CH2:16]2)[CH2:3][CH2:2]1

참가 물질

3

반응물 2

HCID 70770Ethyl 4-piperidinecarboxylateHCID 123114Cyclopropanecarboxaldehyde

생성물 1

HCID 162440151-(Cyclopropylmethyl)piperidine-4-carboxylic acid

실험 절차

The title compound was prepared from cyclopropanecarboxaldehyde and ethyl isonipecotate using similar procedures to those described for Example E15.

출처 및 근거

ORD 기록
ord-946adcaae1bb44ad9d302b3c1b6a754a
출처 데이터셋
uspto-grants-2012_06
특허 번호
US08202858B2

반응 노트

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