Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetyl chloride → Methyl 4-Amino-2-chlorobenzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetyl chloride | HCID 6367 | — |
| 반응물 | 4-Amino-2-chlorobenzoic acid | HCID 17154 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | Methyl 4-Amino-2-chlorobenzoate | HCID 11839197 | — |
반응 단계
A solution of 4-Amino-2-chloro-benzoic acid (5.3 g, 31 mmol) in methanol (100 ml) was treated with acetyl chloride (5 ml) and then heated at reflux for 16 hours. The solvents were evaporated in vacuo. The residue was dissolved in EtOAc, washed with saturated sodium hydrogen carbonate, dried and concentrated in vacuo to yield the title compound as a purple solid, 5.45 g, 95%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08202858B2 |
| 출처 데이터셋 | uspto-grants-2012_06 |
| ORD ID | ord-54db863b2afa414085e0648f08ae77ca |
| 출처 메모 | uspto-grants-2012_06 |