3-Chloro-4-fluorophenylboronic Acid (contains varying amounts of Anhydride) → 2-(3-Chloro-4-fluorophenyl)-4-(4-pyridylmethyl)aniline

HRID 2209470

반응식

HRID 2209470 반응식
Br[C:2]1[CH:8]=[C:7]([CH2:9][C:10]2[CH:15]=[CH:14][N:13]=[CH:12][CH:11]=2)[CH:6]=[CH:5][C:3]=1[NH2:4].[Cl:16][C:17]1[CH:18]=[C:19](B(O)O)[CH:20]=[CH:21][C:22]=1[F:23]>>[Cl:16][C:17]1[CH:18]=[C:19]([C:2]2[CH:8]=[C:7]([CH2:9][C:10]3[CH:15]=[CH:14][N:13]=[CH:12][CH:11]=3)[CH:6]=[CH:5][C:3]=2[NH2:4])[CH:20]=[CH:21][C:22]=1[F:23]

참가 물질

3

반응물 2

HCID 27346603-Chloro-4-fluorophenylboronic Acid (contains varying amounts of Anhydride)HCID 218656452-bromo-4-(4-pyridinylmethyl)Benzenamine

생성물 1

HCID 193812072-(3-Chloro-4-fluorophenyl)-4-(4-pyridylmethyl)aniline

실험 절차

2-bromo-4-(4-pyridylmethyl)aniline and 3-chloro-4-fluorobenzene boronic acid were combined to form 2-(3-chloro-4-fluorophenyl)-4-(4-pyridylmethyl)aniline,

출처 및 근거

ORD 기록
ord-cc42e0ec24c54bc5aa7b45510c6c2a41
출처 데이터셋
uspto-grants-1995_10
특허 번호
US05455252

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