Trichloro(chloromethyl)silane → Chloromethyldichloro(4-fluorophenyl)silane

HRID 2209827노트

반응식

HRID 2209827 반응식
[Cl:1][CH2:2][Si:3]([Cl:6])(Cl)[Cl:4].[F:7][C:8]1[CH:13]=[CH:12][C:11]([Mg]Br)=[CH:10][CH:9]=1>C1COCC1>[Cl:1][CH2:2][Si:3]([Cl:6])([Cl:4])[C:11]1[CH:12]=[CH:13][C:8]([F:7])=[CH:9][CH:10]=1

참가 물질

4

반응물 2

HCID 15258Trichloro(chloromethyl)silaneHCID 178418676HCID 178418676, 화합물

생성물 1

HCID 19382008Chloromethyldichloro(4-fluorophenyl)silane

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

In the same apparatus as Example 1, was added 5.6 g of chloromethyltrichlorosilane (0.03 mol) and 50 ml of THF. Through the dropping funnel was firstly added 22 ml of 4-fluorophenylmagnesiumbromide (2.0 M in diethylether) to give chloromethyldichloro(4-fluorophenyl)silane.

출처 및 근거

ORD 기록
ord-9a42c4cfd268423fa50241803e4fe507
출처 데이터셋
uspto-grants-1995_10
특허 번호
US05455356

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