Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-(Tributylstannyl)pyridine → 1-(beta-D-glucopyranosyl)-4-chloro-3-(5-(3-pyridyl)-2-thienylmethyl)benzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-(Tributylstannyl)pyridine | HCID 3483848 | — |
| 반응물 | 1-(2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl)-4-chloro-3-(5-chloro-2-thienylmethyl)benzene | HCID 66608207 | — |
| 생성물 | 1-(beta-D-glucopyranosyl)-4-chloro-3-(5-(3-pyridyl)-2-thienylmethyl)benzene | HCID 69624867 | — |
반응 단계
1-(β-D-glucopyranosyl)-4-chloro-3-(5-chloro-2-thienylmethyl)benzene obtained in Example 19 was used and treated in a manner similar to Example 106-(1) to give 1-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-4-chloro-3-(5-chloro-2-thienylmethyl)benzene as colorless crystals. APCI-Mass m/Z 590/592 (M+NH4). (2) The above 1-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-4-chloro-3-(5-chloro-2-thienylmethyl)benzene and tri-n-butyl(3-pyridyl)tin were used and treated in a manner similar to Example 124 to give the target compound as colorless powder. APCI-Mass m/Z 448/450 (M+H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08202984B2 |
| 출처 데이터셋 | uspto-grants-2012_06 |
| ORD ID | ord-04bbdb0eb28649859c6fee314a4b0e10 |
| 출처 메모 | uspto-grants-2012_06 |