Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phthalic Acid → 4-[3-(2-Carboxybenzoylamino)propylthio]pyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phthalic Acid | HCID 1017 | — |
| 반응물 | 4-(3-Aminopropylthio)pyridine | HCID 15227695 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 4-[3-(2-Carboxybenzoylamino)propylthio]pyridine | HCID 19079108 | 92.3% |
반응 단계
A solution of 340 mg (2.02 mmol) of 4-(3-aminopropylthio)pyridine and 738 mg (4.98 mmol) of anhydrous phthalic acid in 5 ml of methylene chloride was stirred at room temperature for 30 minutes. The resulting crystals were filtered and dried to obtain 590 mg of the desired compound (92.3%, colorless powder), mp: 151.0°-153.3° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05457106 |
| 출처 데이터셋 | uspto-grants-1995_10 |
| ORD ID | ord-7a3ff4c3da6d4209a50b11a20382f399 |
| 출처 메모 | uspto-grants-1995_10 |