4-Fluoro-N-(2,2,4,6,7-pentamethyl-3-(4-methylphenyl)-2,3-dihydro-1-benzofuran-5-yl]benzamide → N-(4-Fluorobenzyl)-2,2,4,6,7-pentamethyl-3-(4-methylphenyl)-2,3-dihydro-1-benzofuran-5-amine

HRID 2211781노트

반응식

HRID 2211781 반응식
[F:1][C:2]1[CH:31]=[CH:30][C:5]([C:6]([NH:8][C:9]2[C:10]([CH3:29])=[C:11]([CH3:28])[C:12]3[O:16][C:15]([CH3:18])([CH3:17])[CH:14]([C:19]4[CH:24]=[CH:23][C:22]([CH3:25])=[CH:21][CH:20]=4)[C:13]=3[C:26]=2[CH3:27])=O)=[CH:4][CH:3]=1>CO>[F:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:6][NH:8][C:9]2[C:10]([CH3:29])=[C:11]([CH3:28])[C:12]3[O:16][C:15]([CH3:18])([CH3:17])[CH:14]([C:19]4[CH:24]=[CH:23][C:22]([CH3:25])=[CH:21][CH:20]=4)[C:13]=3[C:26]=2[CH3:27])=[CH:30][CH:31]=1

참가 물질

3

반응물 1

HCID 102020944-Fluoro-N-(2,2,4,6,7-pentamethyl-3-(4-methylphenyl)-2,3-dihydro-1-benzofuran-5-yl]benzamide

생성물 1

HCID 9931024N-(4-Fluorobenzyl)-2,2,4,6,7-pentamethyl-3-(4-methylphenyl)-2,3-dihydro-1-benzofuran-5-amine수율 39%

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

By using 4-fluoro-N-[2,2,4,6,7-pentamethyl-3-(4-methylphenyl)-2,3-dihydro-1-benzofuran-5-yl]benzamide, the title compound was synthesized according to Example 2b. Yield: 39%. Melting point: 92-94° C. (Methanol).

출처 및 근거

ORD 기록
ord-7ba0ff826a4f40e297ca69f096e4867f
출처 데이터셋
uspto-grants-2006_09
특허 번호
US07101867B2

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