1-(Bromomethyl)-4-(trifluoromethoxy)benzene → tert-Butyl 4-[(Benzyloxy)methyl]hexahydro-3-oxo-2-[4-(trifluoromethoxy)benzyl]-1H-1,4-diazepine-1-carboxylate

HRID 2211841

반응식

HRID 2211841 반응식
[CH2:1]([O:8][CH2:9][N:10]1[CH2:16][CH2:15][CH2:14][N:13]([C:17]([O:19][C:20]([CH3:23])([CH3:22])[CH3:21])=[O:18])[CH2:12][C:11]1=[O:24])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:25][C:26]([F:37])([F:36])[O:27][C:28]1[CH:35]=[CH:34][C:31]([CH2:32]Br)=[CH:30][CH:29]=1>>[CH2:1]([O:8][CH2:9][N:10]1[CH2:16][CH2:15][CH2:14][N:13]([C:17]([O:19][C:20]([CH3:21])([CH3:23])[CH3:22])=[O:18])[CH:12]([CH2:32][C:31]2[CH:34]=[CH:35][C:28]([O:27][C:26]([F:25])([F:36])[F:37])=[CH:29][CH:30]=2)[C:11]1=[O:24])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

3

반응물 2

HCID 1427851-(Bromomethyl)-4-(trifluoromethoxy)benzeneHCID 21962085tert-Butyl 4-[(Benzyloxy)methyl]hexahydro-3-oxo-1H-1,4-diazepine-1-carboxylate

생성물 1

HCID 21962099tert-Butyl 4-[(Benzyloxy)methyl]hexahydro-3-oxo-2-[4-(trifluoromethoxy)benzyl]-1H-1,4-diazepine-1-carboxylate

실험 절차

The title compound was prepared from tert-butyl 4-[(benzyloxy)methyl]hexahydro-3-oxo-1H-1,4-diazepine-1-carboxylate and 4-(trifluoromethoxy)benzylbromide essentially following the procedure described in Example 3, Step 1.

출처 및 근거

ORD 기록
ord-a85f5c8895684f5aaeec6439fc6ef137
출처 데이터셋
uspto-grants-2006_09
특허 번호
US07101871B2

연결된 노트

불러오는 중…