(3-((Methylsulfonyl)amino)phenyl)acetic acid → HCID 68881619, 화합물

HRID 2212014노트

반응식

HRID 2212014 반응식
[Cl:1][C:2]1[S:6][C:5]([CH2:7][N:8]2[CH2:13][CH2:12][O:11][C@@H:10]([CH2:14][NH2:15])[CH2:9]2)=[CH:4][CH:3]=1.[CH3:16][S:17]([NH:20][C:21]1[CH:22]=[C:23]([CH2:27][C:28](O)=[O:29])[CH:24]=[CH:25][CH:26]=1)(=[O:19])=[O:18]>>[Cl:1][C:2]1[S:6][C:5]([CH2:7][N:8]2[CH2:13][CH2:12][O:11][C@@H:10]([CH2:14][NH:15][C:28](=[O:29])[CH2:27][C:23]3[CH:24]=[CH:25][CH:26]=[C:21]([NH:20][S:17]([CH3:16])(=[O:18])=[O:19])[CH:22]=3)[CH2:9]2)=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 2773885(3-((Methylsulfonyl)amino)phenyl)acetic acidHCID 68881347HCID 68881347, 화합물

생성물 1

HCID 68881619HCID 68881619, 화합물수율 55%

실험 절차

Example 49 was prepared in an analogous manner to Example 44 using a mixture of Intermediate 14 (0.1 g) and Intermediate 18 (0.1 g) to give the title compound (0.102 g).

후처리

  1. customExample 49 was prepared in an analogous manner to Example 44 using

출처 및 근거

ORD 기록
ord-4f5330d8162c4f51a8c1a7c368cc70aa
출처 데이터셋
uspto-grants-2006_09
특허 번호
US07101882B2

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