(3-((Methylsulfonyl)amino)phenyl)acetic acid → HCID 68880571, 화합물

HRID 2212015

반응식

HRID 2212015 반응식
[Cl:1][C:2]1[S:6][C:5]([CH2:7][N:8]2[CH2:13][CH2:12][O:11][C@H:10]([CH2:14][NH2:15])[CH2:9]2)=[CH:4][CH:3]=1.[CH3:16][S:17]([NH:20][C:21]1[CH:22]=[C:23]([CH2:27][C:28](O)=[O:29])[CH:24]=[CH:25][CH:26]=1)(=[O:19])=[O:18]>>[Cl:1][C:2]1[S:6][C:5]([CH2:7][N:8]2[CH2:13][CH2:12][O:11][C@H:10]([CH2:14][NH:15][C:28](=[O:29])[CH2:27][C:23]3[CH:24]=[CH:25][CH:26]=[C:21]([NH:20][S:17]([CH3:16])(=[O:18])=[O:19])[CH:22]=3)[CH2:9]2)=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 2773885(3-((Methylsulfonyl)amino)phenyl)acetic acidHCID 68881532HCID 68881532, 화합물

생성물 1

HCID 68880571HCID 68880571, 화합물수율 45.8%

실험 절차

Example 50 was prepared in an analogous manner to Example 44 using a mixture of Intermediate 14A (0.1 g) and Intermediate 18(0.1 g) to give the title compound (0.085 g).

후처리

  1. customExample 50 was prepared in an analogous manner to Example 44 using

출처 및 근거

ORD 기록
ord-716c7d99ee114564b1c08488e190efa3
출처 데이터셋
uspto-grants-2006_09
특허 번호
US07101882B2

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