4-(Trifluoromethyl)piperidine → 1-(4-Benzenesulfonylbutyl)-4-trifluoromethylpiperidine

반응식

Br[CH2:2][CH2:3][CH2:4][CH2:5][S:6]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)(=[O:8])=[O:7].[F:15][C:16]([F:24])([F:23])[CH:17]1[CH2:22][CH2:21][NH:20][CH2:19][CH2:18]1>>[C:9]1([S:6]([CH2:5][CH2:4][CH2:3][CH2:2][N:20]2[CH2:21][CH2:22][CH:17]([C:16]([F:24])([F:23])[F:15])[CH2:18][CH2:19]2)(=[O:8])=[O:7])[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

참가 물질

반응물 2

HCID 1364694-(Trifluoromethyl)piperidine

HCID 114827894-Phenylsulfonylbutyl bromide

생성물 1

HCID 696634961-(4-Benzenesulfonylbutyl)-4-trifluoromethylpiperidine

실험 절차

Prepared from (4-bromobutane-1-sulfonyl)benzene and 4-trifluoromethylpiperidine by the method in Example 1.

출처 및 근거

ORD 기록: ord-d11c0e537cbd48a1a0e4634c3226eb9a
출처 데이터셋: uspto-grants-2006_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07101892B2

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