N-(3-bromopropyl)-2,2-diphenylacetamide → N-[4-(1-{3-[(diphenylacetyl)amino]propyl}4-piperidinyl)phenyl]-2-methylpropanamide

HRID 2213514

반응식

HRID 2213514 반응식
Br[CH2:2][CH2:3][CH2:4][NH:5][C:6](=[O:20])[CH:7]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.[CH3:21][CH:22]([CH3:38])[C:23]([NH:25][C:26]1[CH:31]=[CH:30][C:29]([CH:32]2[CH2:37][CH2:36][NH:35][CH2:34][CH2:33]2)=[CH:28][CH:27]=1)=[O:24]>>[C:8]1([CH:7]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:6]([NH:5][CH2:4][CH2:3][CH2:2][N:35]2[CH2:36][CH2:37][CH:32]([C:29]3[CH:30]=[CH:31][C:26]([NH:25][C:23](=[O:24])[CH:22]([CH3:21])[CH3:38])=[CH:27][CH:28]=3)[CH2:33][CH2:34]2)=[O:20])[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

참가 물질

3

반응물 2

HCID 21957140N-(3-bromopropyl)-2,2-diphenylacetamideHCID 219572582-methyl-N-[4-(4-piperidinyl)phenyl]propanamide

생성물 1

HCID 21957230N-[4-(1-{3-[(diphenylacetyl)amino]propyl}4-piperidinyl)phenyl]-2-methylpropanamide

실험 절차

Example 148 was prepared from N-(3-bromopropyl)-2,2-diphenylacetamide and 2-methyl-N-[4-(4-piperidinyl)phenyl]propanamide according to the procedures described in Scheme 14: ESMS m/e: 498.3 (M+H)+.

출처 및 근거

ORD 기록
ord-9f0ba7e157b243a2b6176b28ecea06a3
출처 데이터셋
uspto-grants-2006_09
특허 번호
US07105544B2

연결된 노트

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