Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 2-(3-Nitrophenyl)-2-oxoethyl acetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | 2-Bromo-1-(3-nitrophenyl)ethan-1-one | HCID 75213 | — |
| 반응물 | Sodium Acetate | HCID 517045 | — |
| 용매 | Methyl Ethyl Ketone | HCID 6569 | — |
| 생성물 | 2-(3-Nitrophenyl)-2-oxoethyl acetate | HCID 13173800 | 87.5% |
반응 단계
2-Bromo-1-(3-nitrophenyl)ethanone (25 g) was dissolved in methylethyl ketone (150 mL). NaOAc (12.5 g) was added and the mixture stirred for 48 hours. Water (100 mL) was added and the reaction mixture extracted with DCM. The DCM layer was dried over Na2SO4 and concentrated to give the title compound (20 g, 87%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08207167B2 |
| 출처 데이터셋 | uspto-grants-2012_06 |
| ORD ID | ord-125495b67b2042a49067997dd3748cf8 |
| 출처 메모 | uspto-grants-2012_06 |