Ammonium thiocyanate → (4-Ethenylphenyl)methyl thiocyanate

HRID 2214315

반응식

HRID 2214315 반응식
[S-:1][C:2]#[N:3].[NH4+].[CH:5]([C:7]1[CH:14]=[CH:13][C:10]([CH2:11]Cl)=[CH:9][CH:8]=1)=[CH2:6]>CC(C)=O>[CH:5]([C:7]1[CH:14]=[CH:13][C:10]([CH2:11][S:1][C:2]#[N:3])=[CH:9][CH:8]=1)=[CH2:6]

참가 물질

4

반응물 2

HCID 15666Ammonium thiocyanateHCID 74126p-Vinylbenzyl chloride

생성물 1

HCID 15217596(4-Ethenylphenyl)methyl thiocyanate수율 59.3%

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

Ammonium thiocyanate (2 equiv., 43 g, 0.50 mol) was dissolved in acetone (200 ml) and 4-vinylbenzyl chloride (43 g, 0.25 mol) was added to the reaction flask. The mixture was stirred at room temperature overnight. The reaction mixture was filtered and acetone removed under reduced pressure. The resulting product was dissolved in hexane, filtered, and the solvent removed under reduced pressure. The monomer was isolated as a red-orange, slightly viscous liquid (26 g, yield 52%). 1H NMR (CDCl3) δ (ppm) 4.13 (s, 2H), 5.29 (d, 1H), 5.76 (d, 1H), 6.67 (dd, 1H), 7.31 (m, 4H).

후처리

  1. filtrationThe reaction mixture was filtered
  2. customacetone removed under reduced pressure
  3. dissolutionThe resulting product was dissolved in hexane
  4. filtrationfiltered
  5. customthe solvent removed under reduced pressure

출처 및 근거

ORD 기록
ord-887688a7701a42f2aa7cc3951afdc13b
출처 데이터셋
uspto-grants-2006_09
특허 번호
US07108033B2

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