Ammonium thiocyanate → (4-Ethenylphenyl)methyl thiocyanate
반응식
[S-:1][C:2]#[N:3].[NH4+].[CH:5]([C:7]1[CH:14]=[CH:13][C:10]([CH2:11]Cl)=[CH:9][CH:8]=1)=[CH2:6]>CC(C)=O>[CH:5]([C:7]1[CH:14]=[CH:13][C:10]([CH2:11][S:1][C:2]#[N:3])=[CH:9][CH:8]=1)=[CH2:6]참가 물질
4
실험 절차
Ammonium thiocyanate (2 equiv., 43 g, 0.50 mol) was dissolved in acetone (200 ml) and 4-vinylbenzyl chloride (43 g, 0.25 mol) was added to the reaction flask. The mixture was stirred at room temperature overnight. The reaction mixture was filtered and acetone removed under reduced pressure. The resulting product was dissolved in hexane, filtered, and the solvent removed under reduced pressure. The monomer was isolated as a red-orange, slightly viscous liquid (26 g, yield 52%). 1H NMR (CDCl3) δ (ppm) 4.13 (s, 2H), 5.29 (d, 1H), 5.76 (d, 1H), 6.67 (dd, 1H), 7.31 (m, 4H).
후처리
- filtrationThe reaction mixture was filtered
- customacetone removed under reduced pressure
- dissolutionThe resulting product was dissolved in hexane
- filtrationfiltered
- customthe solvent removed under reduced pressure
출처 및 근거
- ORD 기록
- ord-887688a7701a42f2aa7cc3951afdc13b
- 출처 데이터셋
- uspto-grants-2006_09
- 특허 번호
- US07108033B2
반응 노트
불러오는 중…