Hydrazinium chloride → HCID 178468624, 화합물

HRID 2214748노트

반응식

HRID 2214748 반응식
[F:1][C:2]1[C:7]([F:8])=[CH:6][CH:5]=[CH:4][C:3]=1[C:9](=O)[CH2:10][C:11](O)([C:17]([O:19][CH2:20][CH3:21])=[O:18])[C:12](OCC)=[O:13].Cl.[NH2:25][NH2:26]>C(O)C>[F:1][C:2]1[C:7]([F:8])=[CH:6][CH:5]=[CH:4][C:3]=1[C:9]1[N:26]=[N:25][C:12]([OH:13])=[C:11]([C:17]([O:19][CH2:20][CH3:21])=[O:18])[CH:10]=1

참가 물질

4

반응물 2

HCID 115031Hydrazinium chlorideHCID 21948264Diethyl 2-[2-(2,3-difluorophenyl)-2-oxoethyl]-2-hydroxymalonate

생성물 1

HCID 178468624HCID 178468624, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

Diethyl 2-[2-(2,3-difluorophenyl)-2-oxoethyl]-2-hydroxymalonate (18.50 g, 56.1 mmol) and hydrazine monohydrochloride (4.03 g, 58.8 mmol) were stirred at reflux in ethanol (300 mL) for 96 h, and then evaporated to dryness to afford the title compound as a solid.

후처리

  1. customevaporated to dryness

출처 및 근거

ORD 기록
ord-cdc60d1b2bbc4c56998918f30569d2e0
출처 데이터셋
uspto-grants-2006_09
특허 번호
US07109199B2

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