HCID 21055320, 화합물 → HCID 21055321, 화합물

반응식

C[C@H](CSC1C=CC=CC=1OC)CO.[CH2:15]([C@H:17]([CH2:20][S:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=1[O:28][CH3:29])[CH2:18][OH:19])[CH3:16]>>[CH2:15]([C@H:17]([CH2:20][S:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=1[O:28][CH3:29])[CH:18]=[O:19])[CH3:16]

참가 물질

반응물 2

HCID 21055320HCID 21055320, 화합물

HCID 21055336HCID 21055336, 화합물

생성물 1

HCID 21055321HCID 21055321, 화합물

실험 절차

The title compound (IId-1) is obtained by carrying out the preparation as in example 7 but by replacing, in stage 2, 2-(S)-methyl-3-(2-methoxyphenylthio)propan-1-ol (XXb-1) with 2-(S)-ethyl-3-(2-methoxy-phenylthio)propan-1-ol (XXd-1). This title compound, like the aldehyde (IIb-1), is not isolated but is used in situ in the following reductive amination reaction.

후처리

customthe preparation as in example 7

출처 및 근거

ORD 기록: ord-4d2a95291f04459285c1a35ac27b51f7
출처 데이터셋: uspto-grants-2006_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07109234B2

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