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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2215735생성일: 2026년 10월 26일

2-(Methylsulfonyl)ethanamine → N-[4-(benzyloxy)phenyl]-6-[4-({[2-(methanesulphonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine

https://huagongshe.com/reaction/2215735

반응식

참여 물질

역할이름HCID투입량
반응물2-(Methylsulfonyl)ethanamineHCID 4340561—
반응물5-(4-{4-Benzyloxyanilino}-6-quinazolinyl)-furan-3-carbaldehydeHCID 21952275—
생성물N-[4-(benzyloxy)phenyl]-6-[4-({[2-(methanesulphonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamineHCID 9828335—

반응 단계

Prepared according to Procedure D from 5-(4-{4-benzyloxyanilino}-6-quinazolinyl)-furan-3-carbaldehyde (0.6 equiv) and 2-methanesulphonyl-ethylamine (1 equiv). 1HNMR 400 MHz, d6DMSO 9.51 (bs,2H), 9.11 (s, 1H), 8.79 (s, 1H), 8.29 (d, 1H), 8.06 (s, 1H), 7.90 (d, 1H), 7.60 (d, 2H), 7.5–7.3 (m, 5H), 7.11 (d, 2H), 5.14 (s, 2H), 4.14 (bs, 2H), 3.6–3.5 (m, 3H), 3.12 (s, 3H); MS m/z 529 (M+1).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07109333B2
출처 데이터셋uspto-grants-2006_09
ORD IDord-fc204589d30d402a9e8bc62165f9ae35
출처 메모uspto-grants-2006_09