Isopentadecan-1-ol → 13-methyltetradecanal

HRID 2215874노트

반응식

HRID 2215874 반응식
[CH3:1][CH:2]([CH3:16])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][OH:15]>ClCCl>[CH3:1][CH:2]([CH3:16])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH:14]=[O:15]

참가 물질

3

반응물 1

HCID 94094Isopentadecan-1-ol

생성물 1

HCID 1108550713-methyltetradecanal수율 51%

시약·촉매·용매 1

HCID 6344Dichloromethane용매2회

실험 절차

Chloro-chromic pyridine (161.6 g, 0.75 mole) and 450 ml dichloromethane were added to a flask. With stirring, 150 ml dichloromethane solution of 13-methyl-1-tetradecanol (114 g, 0.50 mole) was slowly added to the flask and stirring continued for 1.5 hours at room temperature. Let the mixture stand and separate into two phases. Decant upper phase and wash the remainder with 100 ml diethyl ether. Combine all liquid and wash sequentially with saturated NaCl, 10% HCl, and saturated NaCl solution with 5% NaHCO3. Desiccate with anhydrous CaCl2 and remove solvent by evaporation to yield 13-methyl-tetradecanaldehyde (57.6 g, yield rate 51%).

후처리

  1. stirringstirring
  2. customseparate into two phases
  3. customDecant upper phase
  4. washwash the remainder with 100 ml diethyl ether
  5. washCombine all liquid and wash sequentially with saturated NaCl, 10% HCl, and saturated NaCl solution with 5% NaHCO3
  6. customDesiccate with anhydrous CaCl2 and remove solvent
  7. customby evaporation

출처 및 근거

ORD 기록
ord-d903c0b942024688b9098a2f5c07d6cf
출처 데이터셋
uspto-grants-2006_09
특허 번호
US07109364B2

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