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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2215913생성일: 2026년 10월 25일

(4aS,9bR)-8-bromo-5-methyl-6-trifluoromethyl-1,3,4,4a,5,9b-hexahydro-pyrido[4,3-b]indole-2-carboxylic acid tert-butyl ester → (4aS,9bR)-8-butyl-5-methyl-6-trifluoromethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole

https://huagongshe.com/reaction/2215913

반응식

참여 물질

역할이름HCID투입량
반응물(4aS,9bR)-8-bromo-5-methyl-6-trifluoromethyl-1,3,4,4a,5,9b-hexahydro-pyrido[4,3-b]indole-2-carboxylic acid tert-butyl esterHCID 67182365—
반응물HCID 178448256HCID 178448256—
생성물(4aS,9bR)-8-butyl-5-methyl-6-trifluoromethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoleHCID 58700305—

반응 단계

The title compound was prepared by following the general coupling procedure as a colorless oil from (4aS,9bR)-8-bromo-5-methyl-6-trifluoromethyl-1,3,4,4a,5,9b-hexahydro-pyrido[4,3-b]indole-2-carboxylic acid tert-butyl ester (Example 45) and n-butyl zinc bromide. MS (ES+): 313 (base, M+H).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07109339B2
출처 데이터셋uspto-grants-2006_09
ORD IDord-0a54f8a8944b4bc79ae49117938e30e0
출처 메모uspto-grants-2006_09