(2-Chloro-2-oxoethyl)dimethylazanium chloride → {(3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-2-oxo-2,3-dihydro-1H-indol-1-yl}methyl (dimethylamino)acetate

HRID 2216644노트

반응식

HRID 2216644 반응식
[Cl-].Cl[C:3](=[O:8])[CH2:4][NH+:5]([CH3:7])[CH3:6].[CH3:9][C:10]1[CH:14]=[C:13]([CH3:15])[NH:12][C:11]=1/[CH:16]=[C:17]1\[C:18](=[O:28])[N:19]([CH2:26][OH:27])[C:20]2[C:25]\1=[CH:24][CH:23]=[CH:22][CH:21]=2>>[CH3:6][N:5]([CH2:4][C:3]([O:27][CH2:26][N:19]1[C:20]2[C:25](=[CH:24][CH:23]=[CH:22][CH:21]=2)/[C:17](=[CH:16]/[C:11]2[NH:12][C:13]([CH3:15])=[CH:14][C:10]=2[CH3:9])/[C:18]1=[O:28])=[O:8])[CH3:7]

참가 물질

3

반응물 2

HCID 21943384(2-Chloro-2-oxoethyl)dimethylazanium chlorideHCID 178424865HCID 178424865, 화합물

생성물 1

HCID 9946572{(3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-2-oxo-2,3-dihydro-1H-indol-1-yl}methyl (dimethylamino)acetate

실험 절차

Following the procedure of Example 2, the title compound was prepared from 2-chloro-N,N-dimethyl-2-oxoethanaminium chloride and (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)-methylidene]-1-(hydroxymethyl)-1,3-dihydro-2H-indol-2-one (1).

출처 및 근거

ORD 기록
ord-5e876e18566d4a0293bdb1006b2a17f0
출처 데이터셋
uspto-grants-2006_09
특허 번호
US07112603B2

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