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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2217734생성일: 2026년 10월 27일

Dabco → 1-[4'-(4-{1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]4-oxoazetidin-2-yl}phenoxymethyl)biphenyl-4-ylmethyl]-4-aza-1-azoniabicyclo[2.2.2]octane bromide

https://huagongshe.com/reaction/2217734

반응식

참여 물질

역할이름HCID투입량
반응물DabcoHCID 9237—
반응물4-[4-(4'-Bromomethylbiphenyl-4-ylmethoxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]azetidin-2-oneHCID 21083191—
용매TolueneHCID 1140—
생성물1-[4'-(4-{1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]4-oxoazetidin-2-yl}phenoxymethyl)biphenyl-4-ylmethyl]-4-aza-1-azoniabicyclo[2.2.2]octane bromideHCID 21083159—

반응 단계

Compound (21) and DABCO were dissolved in toluene and reacted analogously to Example IV, giving the product (22) as a colorless solid of molecular weight 780.76 (C44H44BrF2N3O3); MS (ESI): 700.3 (MH+).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07407938B2
출처 데이터셋uspto-grants-2008_08
ORD IDord-4eb397d7a6da402285e6c3ab9897071f
출처 메모uspto-grants-2008_08